国际眼科纵览 ›› 2021, Vol. 45 ›› Issue (4): 295-299.doi: 10.3760/ cma.j.issn.1673-5803.2021.04.005

• 综述 • 上一篇    下一篇

球形晶状体的治疗进展

郑佳蕾 邓麦可 蒋永祥   

  1. 复旦大学附属眼耳鼻喉科医院眼科 卫健委/医科院近视眼重点实验室 上海市视觉损伤与修复重点实验室,上海 200031
  • 收稿日期:2020-10-30 出版日期:2021-08-22 发布日期:2021-08-30
  • 通讯作者: 蒋永祥,Email:yongxiang_jiang@163.com E-mail:yongxiang_jiang@163.com
  • 基金资助:
    国家自然科学基金(81770908;82070943);上海市科学技术委员会科技创新行动计划(18411965200)

Treatment of microspherophakia

Zheng Jialei, Deng Michael, Jiang Yongxiang   

  1. Department of Ophthalmology, Eye and ENT Hospital of Fudan University, NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, Chinese Academy of Medical Sciences, Key Laboratory of Visual Impairment and Restoration of Shanghai, Shanghai 200031, China
  • Received:2020-10-30 Online:2021-08-22 Published:2021-08-30
  • Contact: Jiang Yongxiang, Email: yongxiang_jiang@163.com E-mail:yongxiang_jiang@163.com
  • Supported by:
    National Natural Science Foundation of China (81770908; 82070943); Shanghai Science and Technology Commission Scientific Innovation Action Plan (18411965200)

摘要: 球形晶状体是一种罕见的先天性悬韧带晶状体疾病,常见的并发症为晶状体脱位或不全脱位和继发性青光眼,并发症发生时间早,致盲率高,因此尽早的诊断和治疗尤为重要。球形晶状体的治疗主要根据并发症的严重程度而定,可以分为晶状体手术和抗青光眼治疗,晶状体手术包括晶状体吸除+人工晶状体植入术、晶状体吸除+改良囊袋张力环植入+人工晶状体植入术等;抗青光眼手术包括YAG激光虹膜周切术、小梁切除术等。球形晶状体行晶状体手术后视力恢复明显,不同的抗青光眼手术后眼压控制效果不一,手术的长期有效性和安全性还有待观察。(国际眼科纵览,2021, 45: 295-299)

关键词: 球形晶状体, 晶状体不全脱位, 继发性青光眼

Abstract: Microspherophakia is a rare congenital disease characterized by increased anteroposterior diameter and reduced equatorial diameter. The common complications of microspherophakia include crystalline subluxation or dislocation and secondary glaucoma. The complications occur at an early time and lead to a high rate of blindness. Therefore, it's necessary to diagnose and treat the disease at the earliest. The treatment for microspherophakia can be divided into lens surgery and anti-glaucoma treatment. Lens surgery include lens aspiration +intraocular lens (IOL) implantation, lens aspiration + modified capsular tension ring (MCTR) implantation + IOL implantation, etc. Anti-glaucoma operations include YAG laser iridotomy, trabeculectomy and so on. Currently, there is no unified treatment method, and there are many feasible treatment methods according to the severity of complications. The visual acuity recovers obviously after the lens operation, but different anti-glaucoma treatments have different effects on intraocular pressure control. The long-term effectiveness and safety of the treatments remain to be observed. (Int Rev Ophthalmol, 2021, 45: 295-299)

Key words: microspherophakia, subluxation, secondary glaucoma